Inositol phosphates and derivatives

synthesis, biochemistry, and therapeutic potential
  • 235 Pages
  • 0.24 MB
  • 2229 Downloads
  • English

American Chemical Society , Washington, DC
Inositol phosphates -- Congresses., Inositol phosphates -- Derivatives -- Congre
StatementAllen B. Reitz, editor.
GenreCongresses.
SeriesACS symposium series ;, 463
ContributionsReitz, Allen Bernard, 1956-, American Chemical Society. Division of Carbohydrate Chemistry., American Chemical Society. Meeting
Classifications
LC ClassificationsQP772.I5 I58 1991
The Physical Object
Paginationxii, 235 p. :
ID Numbers
Open LibraryOL1539215M
ISBN 100841220867
LC Control Number91017716

Inositol Phosphates and Derivatives: Synthesis, Biochemistry, and Therapeutic Potential (ACS Symposium Series) 1st Edition by Inositol phosphates and derivatives book B. Reitz (Editor) ISBN ISBN Why is ISBN important. ISBN.

This bar-code number lets you verify that you're getting exactly the right version or edition of a book. Format: Hardcover. Biochemistry, stereochemistry, and nomenclature of the inositol phosphates / R. Parthasarathy and F. Eisenberg, Jr. --Phosphoinositides and their stimulated breakdown / B.W.

Agranoff and S.K.

Download Inositol phosphates and derivatives EPUB

Fisher --Enantiospecific synthesis and Ca2+-release activities of some inositol polyphosphates and their derivatives / Clinton E. Ballou and Werner Tegge. Inositol, or more precisely myo-inositol, is Inositol phosphates and derivatives book carbocyclic sugar that is abundant in brain and other mammalian tissues, mediates cell signal transduction in response to a variety of hormones, neurotransmitters and growth factors and participates in osmoregulation.

It is a sugar alcohol with half the sweetness of sucrose (table sugar). It is made naturally in humans from al formula: C₆H₁₂O₆. Biochemistry, stereochemistry, and nomenclature of the inositol phosphates, R. Parthasarathy and F. Eisenberg Jr.; phosphoinositides and their stimulated breakdown, B.W.

Agranoff and S.K. Fisher; enantiospecific synthesis and Ca2+ release activities of some inositol polyphosphates and their derivates, Clinton E.

Ballou and Werner Tegge. Inositol and its phosphates are ubiquitous across most life forms, wherein they play important roles in cellular integrity and functions such as signal transduction, DNA damage repair ion transport and mRNA transport.

This reference details the biochemistry and industrial applications of inositol and its phosphate : Paperback. This chapter covers the myo-inositol phosphates and their glyceryl esters with the exception of phytic acid, which is covered in Chapter 2, and of phosphatidylinositol (PI) and its derivatives, which are covered in Chapter following is a complete list.

In Laboratory Techniques in Biochemistry and Molecular Biology, Inositol phosphate phosphatases. Theoretically, the phosphatases, which have shown stereospecificity could have been used to establish the chirality of the inositol phosphates, but no specific applications appear to have been made.A large family of 5-phosphates has been identified in the soluble and in.

Details Inositol phosphates and derivatives FB2

Inositol phosphates are a group of organic compounds found widely in the natural environment. They are important in agriculture because they constitute most of the phosphorus in grain seeds, but they cannot be digested by some animals.

As a result, considerable research has been directed towards improving the digestibility of inositol phosphates in animal diets. NEXT BOOK; VIEW ALL BOOKS ALL BOOKS; Inositol Phosphates and Derivatives Synthesis, Biochemistry, and Therapeutic Potential.

Editor(s): Allen B. Reitz 1; Volume Publication Date (Print): Biology-enabling inositol phosphates, phosphatidylinositol phosphates and derivatives Stuart J.

Conway * a and Gavin J. Miller a Author affiliations. A large proportion of endogenous soil P occurs in organic forms, of which derivatives of inositol phosphates constitute a major fraction (Richardson et al., ).

In this book, the authors present topical research in the study of the synthesis, functions and clinical implications of inositol. Topics discussed include hypoxia and angiogenesis related myo-inositol phosphates; inositol derivatives in mycobacterium tuberculosis; inositols and epilepsy; the contribution of inositol trisphosphate signaling to.

Considerable evidence has accumulated indicating a significant role of dietary inositol and its phosphates, and phospholipid derivatives in human health. In a typical American diet, the amount of myo-inositol per kcal diet is approximately mg, and most of the inositol compounds are phospholipid : A.K.M.

Shamsuddin and Guang-Yu Yang. Inositol phosphates are also abundant in soils and water bodies, yet a clear understanding of their behaviour in the environment remains elusive.

Written by leading experts, this book brings together critical reviews on inositol phosphates in agriculture, ecology, and the environment. The sixteen chapters cover a diverse range of topics.

Myo-inositol, infact, is the oldest known inositol and it was isolated from muscle as early as and phytin (Inositol hexakis phosphate) from plants by Pfeffer in Since then, interest in inositols and their derivatives varied as the methodology of isolation and puri?cation of the stereoisomers of inositol and their derivatives advanced.

This reference details the biochemistry and industrial applications of inositol and its phosphate derivatives. Topics covered in this book include the use of inositol and its hexaphosphate (IP6) for numerous health benefits – as antioxidants, as an anti-cancer drug, for the management of atherosclerosis, diabetes, osteoporosis, Alzheimer’s Author: A.K.M.

Shamsuddin, Guang-Yu Yang. Inositol phosphates are also abundant in soils and water bodies, yet a clear understanding of their behaviour in the environment remains elusive.

This is surprising given the importance of phosphorus in the nutrition of both terrestrial and aquatic ecosystems. Written by leading experts, this book brings together critical reviews on inositol. This reference details the biochemistry and industrial applications of inositol and its phosphate derivatives.

Topics covered in this book include the use of inositol and its hexaphosphate (IP6) for numerous health benefits – as antioxidants, as an anti-cancer drug, for the management of atherosclerosis, diabetes, osteoporosis, Alzheimer's. Inositol and its phosphates are ubiquitous across most life forms, wherein they play important roles in cellular integrity and functions such as signal transduction, DNA damage repair ion transport and mRNA transport.

This reference details the biochemistry and industrial applications of inositol and its phosphate : A.K.M. Shamsuddin, Guang-Yu Yang. PDF | On Aug 1,Shoichiro Ozaki and others published Synthesis of Phosphatidyl-myo-inositol Polyphosphate and Derivatives | Find, read and cite. Inositol and its phosphates, specifically InsP6 have antioxidant properties, the latter is a very strong antioxidant indeed.

This is brought about by chelating iron through the Fenton Reaction.

Description Inositol phosphates and derivatives FB2

The exact mechanism how inositol acts as an antioxidant is not clear; however it could be by phosphorylation to inositol phosphates. Inositol hexaphosphate-citrate, a new molecule has.

This book brings together critical reviews on inositol phosphates in agriculture, ecology, and the environment. It includes 16 chapters covering a diverse range of topics, including the synthesis and hydrolysis of inositol phosphates, their role in animal nutrition, and their fate in soils and aquatic ecosystems.

Written by leading experts, this book brings together critical reviews on inositol phosphates in agriculture, ecology, and the environment.

The sixteen chapters cover a diverse range of topics, including the synthesis and hydrolysis of inositol phosphates, their role in animal nutrition, and their fate in soils and aquatic ecosystems.

Inositols, in particular myo-inositol, play a central role in cellular metabolism. An array of complicated molecules that incorporate the inositol moiety are found in nature.

Structural heterogeneity of inositol derivatives is compounded by the presence of stereo- and regioisomers of the inositol by: Chemical Synthesis of Phosphatidylinositol Phosphates and Their Use as Biological Tools Yutaka Watanabe Chap DOI: /bkch Publication Date (Print): Decem In vivo, inositol phosphates are interrelated by a complex web of reactions (Majerus et al., ), and a rapid dynamic equilibrium exists among the different inositol phosphates.

A number of recent reviews (Drøbak,; Coté and Crain, ; Hetherington and Drøbak, ; Rincon and Boss, ) and other chapters in this book contain Cited by: 8.

The role of inositol and the principles of labelling, extraction, and analysis of inositides in mammalian cells. Barker CJ(1), Berggren PO. Author information: (1)The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Stockholm, Sweden.

Inositides have an important impact on diverse areas of cellular by: 3. Six bifunctional molecules containing biotin and various inositol phosphates were synthesized. These compounds were designed on the basis of X-ray structures of the complexes of D-myo-inositol 1,4,5-triphosphates (IP 3) and phospholipase C δ pleckstrin homology domain (PLCδ PH) considering the application to the biotin –avidin techniques.

The building blocks of the inositol. In organic chemistry, a cyclitol is a cycloalkane containing at least three hydroxyl, each attached to a different ring carbon atom.

The general formula for an unsubstituted cyclitol is C n H 2n-x (OH) x or C n H 2n O x where 3 ≤ x ≤ n. The name is also used for compounds that can be viewed as result of substituting various functional groups for the hydrogen atoms in such a. Inositol Phospholipid Metabolism and Phosphatidyl Inositol Kinases A.

Kuksis (Eds.) This book offers a wide ranging and review of cutting edge developments along with tried and tested methods for isolation, resolution and quantification of inositol phospholipids and inositol polyphosphates in both cells and tissues.

Phosphorylated Ins-derivatives [(poly)phosphoinositides and inositol (poly)phosphates] are versatile and dynamic signaling molecules in all eukaryotes, particularly in plants.

These two classes of compounds [highlighted in red and orange respectively, in Figure 1] are interdependent. While (poly)phosphoinositides are used in the synthesis of Cited by: 1.IP4, IP5, and IP6 were known to occur in tissues at concentrations even higher than those of IP3.

In the mids, we were entranced by reports that tissues labeled with [3H]inositol formed IP7, an inositol phosphate in which one of the hydroxyls contains a diphosphate, which, by definition, ought to be a pyrophosphate as energetic as ATP.

Inositol and Reproductive Function. Inositols and their phosphates function as secondary messenger molecules for various cellular signaling pathways including insulin signal transduction, calcium trafficking, lipid metabolism, cytoskeletal protein assembly, cell growth and differentiation, modulation of serotoninergic pathways, oocyte maturation, and fertility [].Cited by: 4.